GrippeAllemagneV3, Main, Exploration, bibRecord, 000322

[Immunosenescence and vaccinations in the elderly].

Identifieur interne : 000322 ( Main/Exploration ); précédent : 000321; suivant : 000323

[Immunosenescence and vaccinations in the elderly].

Auteurs : Hans Joachim Hutt [Allemagne] ; Petra Bennerscheidt ; Britta Thiel ; Manuela Arand

Source :

Medizinische Klinik (Munich, Germany : 1983) [ 1615-6722 ] ; 2010.

RBID : pubmed:21136238

Descripteurs français

KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Allemagne, Calendrier vaccinal, Essais cliniques de phase III comme sujet, Facteurs de l'âge, Femelle, Grippe humaine (), Grippe humaine (immunologie), Humains, Immunocompétence (immunologie), Injections intradermiques, Jeune adulte, Lymphocytes B (immunologie), Lymphocytes T (immunologie), Maladie chronique, Mâle, Pneumonie à pneumocoques (), Pneumonie à pneumocoques (immunologie), Production d'anticorps (immunologie), Rappel de vaccin, Sujet âgé, Sujet âgé de 80 ans ou plus, Vaccins (administration et posologie), Vaccins (immunologie), Vaccins antigrippaux (administration et posologie), Vaccins antigrippaux (immunologie).
MESH :
- administration et posologie : Vaccins, Vaccins antigrippaux.
- immunologie : Grippe humaine, Immunocompétence, Lymphocytes B, Lymphocytes T, Pneumonie à pneumocoques, Production d'anticorps, Vaccins, Vaccins antigrippaux.
- Adolescent, Adulte, Adulte d'âge moyen, Allemagne, Calendrier vaccinal, Essais cliniques de phase III comme sujet, Facteurs de l'âge, Femelle, Grippe humaine, Humains, Injections intradermiques, Jeune adulte, Maladie chronique, Mâle, Pneumonie à pneumocoques, Rappel de vaccin, Sujet âgé, Sujet âgé de 80 ans ou plus.
Wicri :
- geographic : Allemagne.

English descriptors

KwdEn :
- Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Antibody Formation (immunology), B-Lymphocytes (immunology), Chronic Disease, Clinical Trials, Phase III as Topic, Female, Germany, Humans, Immunization Schedule, Immunization, Secondary, Immunocompetence (immunology), Influenza Vaccines (administration & dosage), Influenza Vaccines (immunology), Influenza, Human (immunology), Influenza, Human (prevention & control), Injections, Intradermal, Male, Middle Aged, Pneumonia, Pneumococcal (immunology), Pneumonia, Pneumococcal (prevention & control), T-Lymphocytes (immunology), Vaccines (administration & dosage), Vaccines (immunology), Young Adult.
MESH :
- chemical , administration & dosage : Influenza Vaccines, Vaccines.
- chemical , immunology : Influenza Vaccines, Vaccines.
- geographic : Germany.
- immunology : Antibody Formation, B-Lymphocytes, Immunocompetence, Influenza, Human, Pneumonia, Pneumococcal, T-Lymphocytes.
- prevention & control : Influenza, Human, Pneumonia, Pneumococcal.
- Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Chronic Disease, Clinical Trials, Phase III as Topic, Female, Humans, Immunization Schedule, Immunization, Secondary, Injections, Intradermal, Male, Middle Aged, Young Adult.

Abstract

With increasing age, infection-induced morbidity and mortality rises. At the same time, the protective capacity of the immune system declines. This phenomenon is known as immunosenescence. It concerns all parts of the immune system and leads to a decline of cellular and humoral immune defense. As a consequence, the ability to resist infections and the immune response to vaccinations could be impaired. In order to protect senior citizens effectively against infections with dangerous pathogens like influenza viruses or pneumococci, new immunisation strategies, e.g. with shortened intervals between vaccinations, new vaccines or new vaccination techniques are required. Intradermal vaccines seem to be a promising approach, for instance. At the same time the acceptance of vaccination ought to be increased in the senior age group. Physicians, especially general practitioners play an important role because of their decisive effect on the willingness of the population to get vaccinated.

DOI: 10.1007/s00063-010-1137-0
PubMed: 21136238

Affiliations:

Allemagne

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000314
to stream Main, to step Curation: 000314

Le document en format XML

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<front><div type="abstract" xml:lang="en">With increasing age, infection-induced morbidity and mortality rises. At the same time, the protective capacity of the immune system declines. This phenomenon is known as immunosenescence. It concerns all parts of the immune system and leads to a decline of cellular and humoral immune defense. As a consequence, the ability to resist infections and the immune response to vaccinations could be impaired. In order to protect senior citizens effectively against infections with dangerous pathogens like influenza viruses or pneumococci, new immunisation strategies, e.g. with shortened intervals between vaccinations, new vaccines or new vaccination techniques are required. Intradermal vaccines seem to be a promising approach, for instance. At the same time the acceptance of vaccination ought to be increased in the senior age group. Physicians, especially general practitioners play an important role because of their decisive effect on the willingness of the population to get vaccinated.</div>
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<Reference><Citation>Rejuvenation Res. 2009 Apr;12(2):127-35</Citation>
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<affiliations><list><country><li>Allemagne</li>
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<name sortKey="Bennerscheidt, Petra" sort="Bennerscheidt, Petra" uniqKey="Bennerscheidt P" first="Petra" last="Bennerscheidt">Petra Bennerscheidt</name>
<name sortKey="Thiel, Britta" sort="Thiel, Britta" uniqKey="Thiel B" first="Britta" last="Thiel">Britta Thiel</name>
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<country name="Allemagne"><noRegion><name sortKey="Hutt, Hans Joachim" sort="Hutt, Hans Joachim" uniqKey="Hutt H" first="Hans Joachim" last="Hutt">Hans Joachim Hutt</name>
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[Immunosenescence and vaccinations in the elderly].

[Immunosenescence and vaccinations in the elderly].

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